Recombinant Human FKBP2
| Cat.No. : | FKBP2-28913TH |
| Product Overview : | Recombinant Human full-length mature FKBP2, amino acids 22-142, predicted MWt 13.4 kDa. |
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| Species : | Human |
| Source : | E.coli |
| Tag : | Non |
| Protein Length : | 121 amino acids |
| Description : | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified. |
| Molecular Weight : | 13.400kDa |
| Tissue specificity : | T-cells and thymus. |
| Biological activity : | Specific activity is >150 nmoles/min/ug, and is defined as the amount of enzyme that cleave 1umole of suc-AAFP-pNA per minute at 1C in Tris-Hcl pH8.0 using chymotrypsin. |
| Form : | Liquid |
| Purity : | >90% by SDS-PAGE |
| Storage buffer : | pH: 8.00Constituents:10% Glycerol, 0.32% Tris HCl, 0.02% DTT |
| Storage : | Please see Notes section |
| Sequences of amino acids : | MATGAEGKRK LQIGVKKRVD HCPIKSRKGD VLHMHYTGKL EDGTEFDSSL PQNQPFVFSL GTGQVIKGWD QGLLGMCEGE KRKLVIPSEL GYGERGAPPK IPGGATLVFE VELLKIERRT EL. |
| Sequence Similarities : | Belongs to the FKBP-type PPIase family. FKBP2 subfamily.Contains 1 PPIase FKBP-type domain. |
| Gene Name | FKBP2 FK506 binding protein 2, 13kDa [ Homo sapiens ] |
| Official Symbol | FKBP2 |
| Synonyms | FKBP2; FK506 binding protein 2, 13kDa; FK506 binding protein 2 (13kD); peptidyl-prolyl cis-trans isomerase FKBP2; FKBP 13; peptidyl prolyl cis trans isomerase; PPIase; proline isomerase; rapamycin binding protein; |
| Gene ID | 2286 |
| mRNA Refseq | NM_001135208 |
| Protein Refseq | NP_001128680 |
| MIM | 186946 |
| Uniprot ID | P26885 |
| Chromosome Location | 11q13.1-q13.3 |
| Function | FK506 binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; protein binding; |
| ◆ Recombinant Proteins | ||
| FKBP2-1288H | Active Recombinant Human FK506 Binding Protein 2, 13kDa | +Inquiry |
| FKBP2-734H | Recombinant Human FKBP2 Protein, His-tagged | +Inquiry |
| FKBP2-3268M | Recombinant Mouse FKBP2 Protein, His (Fc)-Avi-tagged | +Inquiry |
| FKBP2-2752H | Recombinant Human FKBP2 Protein (Ala22-Leu142), C-His tagged | +Inquiry |
| FKBP2-28913TH | Recombinant Human FKBP2 | +Inquiry |
| ◆ Cell & Tissue Lysates | ||
| FKBP2-6207HCL | Recombinant Human FKBP2 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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