Recombinant Human FHL1, MYC/DDK-tagged

• Cat.No.: FHL1-128H
• Product Overview: Recombinant Human FHL1, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.
• Molecular Mass: 31.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: FHL1 four and a half LIM domains 1 [ Homo sapiens (human) ]
• Official Symbol: FHL1
• Synonyms: FHL1; four and a half LIM domains 1; KYOT; SLIM; FHL-1; FHL1A; FHL1B; FLH1A; SLIM1; XMPMA; SLIM-1; SLIMMER; four and a half LIM domains protein 1; LIM protein SLIMMER; four-and-a-half Lin11, Isl-1 and Mec-3 domains 1; skeletal muscle LIM-protein 1
• Gene ID: 2273
• mRNA Refseq: NM_001449
• Protein Refseq: NP_001440
• MIM: 300163
• UniProt ID: Q13642
• Chromosome Location: Xq26
• Pathway: Delta-Notch Signaling Pathway
• Function: ion channel binding; molecular_function; protein binding; zinc ion binding