Recombinant Human FDXR protein, His/T7-tagged

• Cat.No.: FDXR-12H
• Product Overview: Recombinant Human FDXR(Ser33~Arg219) fused with His/T7 tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Ser33~Arg219
• Description: This gene encodes a mitochondrial flavoprotein that initiates electron transport for cytochromes P450 receiving electrons from NADPH. Multiple alternatively spliced transcript variants have been found for this gene.
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300
• Molecular Mass: Predicted Molecular Mass: 24.1kDa;
  Accurate Molecular Mass: 24.1kDa(Analysis of differences refer to the manual)
• Endotoxin: Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Purity: > 95%
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: FDXR ferredoxin reductase [ Homo sapiens ]
• Official Symbol: FDXR
• Synonyms: FDXR; ferredoxin reductase; ADXR; NADPH:adrenodoxin oxidoreductase, mitochondrial; AR; adrenodoxin reductase; ferredoxin--NADP(+) reductase
• Gene ID: 2232
• mRNA Refseq: NM_001258012
• Protein Refseq: NP_001244941
• MIM: 103270
• UniProt ID: P22570
• Chromosome Location: 17q24-q25
• Pathway: Direct p53 effectors, organism-specific biosystem
• Function: NADPH binding; NADPH-adrenodoxin reductase activity; ferredoxin-NADP+ reductase activity; nucleotide binding; protein binding