Recombinant Human FCAR protein, His & GST-tagged

• Cat.No.: FCAR-6909H
• Product Overview: Recombinant Human FCAR aa. (Gln22~Asn227 (Accession # P24071)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Gln22~Asn227
• Description: This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 55.9kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.3.
• Applications: SDS-PAGE; WB; ELISA; IP
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: FCAR Fc fragment of IgA receptor [ Homo sapiens (human) ]
• Official Symbol: FCAR
• Synonyms: FCAR; Fc fragment of IgA receptor; CD89; FcalphaRI; CTB-61M7.2; immunoglobulin alpha Fc receptor; FCAR variant 14; Fc alpha receptor; Fc fragment of IgA, receptor for
• Gene ID: 2204
• mRNA Refseq: NM_002000.3
• Protein Refseq: NP_001991.1
• UniProt ID: P24071