Recombinant Human FBXO44, GST-tagged

• Cat.No.: FBXO44-12802H
• Product Overview: Recombinant Human FBXO44 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-224a.a.
• Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Four alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: FBXO44 F-box protein 44 [ Homo sapiens ]
• Official Symbol: FBXO44
• Synonyms: F-box protein 44; 24847; Ensembl:ENSG00000132879; MGC14140, DKFZp781J0852; F-box only protein 44;F-box gene 3;F-box protein FBX30;F-box/G-domain protein 3; FBG3; FBX30; FBX6A; Fbx44; Fbxo6a
• Gene ID: 93611
• mRNA Refseq: NM_001014765.1
• Protein Refseq: NP_001014765.1
• MIM: 609111
• UniProt ID: Q9H4M3
• Chromosome Location: 1p36.22
• Pathway: Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem
• Function: protein binding