Recombinant Human FBXO42, His-tagged

• Cat.No.: FBXO42-12801H
• Product Overview: Recombinant Human FBXO42 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: Members of the F-box protein family, such as FBXO42, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (SKP1A; MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-343a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FBXO42 F-box protein 42 [ Homo sapiens ]
• Official Symbol: FBXO42
• Synonyms: FBXO42; F-box protein 42; F-box only protein 42; Fbx42; KIAA1332; just one F-box and Kelch domain-containing protein; JFK
• Gene ID: 54455
• mRNA Refseq: NM_018994
• Protein Refseq: NP_061867
• MIM: 609109
• UniProt ID: Q6P3S6
• Chromosome Location: 1p36.23-p36.11