Recombinant Human FBXL5 Protein, GST-His-tagged

• Cat.No.: FBXL5-479H
• Product Overview: Recombinant Human FBXL5, transcript variant 2, fused with N-terminal GST and C-terminal His was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Description: THis gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by tHis gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for tHis locus.
• Form: 25mM Tris, pH8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 91.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: FBXL5 F-box and leucine-rich repeat protein 5 [ Homo sapiens ]
• Official Symbol: FBXL5
• Synonyms: FBXL5; F-box and leucine-rich repeat protein 5; F-box/LRR-repeat protein 5; FBL4; FBL5; FLR1; F-box protein FBL5; p45SKP2-like protein; F-box protein FBL4/FBL5
• Gene ID: 26234
• mRNA Refseq: NM_001193534
• Protein Refseq: NP_001180463
• MIM: 605655
• UniProt ID: Q9UKA1