Recombinant Human FBXL20, His-tagged

• Cat.No.: FBXL20-12778H
• Product Overview: Recombinant Human FBXL20 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: C-term-357a.a.
• Description: Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FBXL20 F-box and leucine-rich repeat protein 20 [ Homo sapiens ]
• Official Symbol: FBXL20
• Synonyms: FBXL20; F-box and leucine-rich repeat protein 20; F-box/LRR-repeat protein 20; Fbl2; Fbl20; MGC15482; F-box protein FBL2; FLJ21037; DKFZp564O2364
• Gene ID: 84961
• mRNA Refseq: NM_001184906
• Protein Refseq: NP_001171835
• MIM: 609086
• UniProt ID: Q96IG2
• Chromosome Location: 17q21.2