Recombinant Human FBXL18, GST-tagged

• Cat.No.: FBXL18-12775H
• Product Overview: Recombinant Human FBXL18 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Members of the F-box protein family, such as FBXL18, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: N-term-365a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: FBXL18 F-box and leucine-rich repeat protein 18 [ Homo sapiens ]
• Official Symbol: FBXL18
• Synonyms: FBXL18; F-box and leucine-rich repeat protein 18; F-box/LRR-repeat protein 18; Fbl18; FLJ11467; FLJ10776; FLJ26934; FLJ38075; FLJ41541
• Gene ID: 80028
• mRNA Refseq: NM_024963
• Protein Refseq: NP_079239
• MIM: 609084
• UniProt ID: Q96ME1
• Chromosome Location: 7p22.2