Recombinant Human FBN1 Over-expression Lysate, C-Myc/DDK tagged

• Cat.No.: FBN1-01HCL
• Product Overview: Recombinant Human FBN1 Over-expression Lysate with C-Myc/DDK tag was expressed in HEK293T.
  Components: 1 vial of 20 μg lyophilized gene specific transient over-expression cell lysate

Specification

• Description: This gene encodes a member of the fibrillin family of proteins. The encoded preproprotein is proteolytically processed to generate two proteins including the extracellular matrix component fibrillin-1 and the protein hormone asprosin. Fibrillin-1 is an extracellular matrix glycoprotein that serves as a structural component of calcium-binding microfibrils. These microfibrils provide force-bearing structural support in elastic and nonelastic connective tissue throughout the body. Asprosin, secreted by white adipose tissue, has been shown to regulate glucose homeostasis. Mutations in this gene are associated with Marfan syndrome and the related MASS phenotype, as well as ectopia lentis syndrome, Weill-Marchesani syndrome, Shprintzen-Goldberg syndrome and neonatal progeroid syndrome.
• Source: HEK293T
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 312.24 kDa
• Applications: WB positive control
• Stability: Lysate samples are stable for 12 months from date of receipt when stored at -20 centigrade.
• Storage: Upon receiving, store the sample at -20 centigrade. Avoid repeated freeze-thaw cycles after reconstitution.
• Reconstitution: Lysate samples can be reconstituted with SDS Sample Buffer.
• Shipping: The lysate can be shipped at ambient temperature.

Gene Information

• Gene Name: FBN1 fibrillin 1 [ Homo sapiens (human) ]
• Official Symbol: FBN1
• Synonyms: FBN1; fibrillin 1; FBN; SGS; WMS; MASS; MFLS; MFS1; OCTD; SSKS; WMS2; ACMICD; ECTOL1; GPHYSD2; fibrillin-1; asprosin; epididymis secretory sperm binding protein; fibrillin 15; fibrillin-1 preproprotein
• Gene ID: 2200
• mRNA Refseq: NM_000138
• Protein Refseq: NP_000129
• MIM: 134797
• UniProt ID: P35555