Recombinant Human FASTK Protein, His-tagged

• Cat.No.: FASTK-01H
• Product Overview: Recombinant human FASTK (200-535) protein with a N-terminal His-tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 38.2 kDa
• Protein length: 200-535
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade
• Concentration: > 50 µg/mL as determined by microplate BCA method
• Storage Buffer: 50mM Tris, 8M Urea, pH8.0

Gene Information

• Gene Name: FASTK Fas activated serine/threonine kinase [ Homo sapiens (human) ]
• Official Symbol: FASTK
• Synonyms: FASTK; Fas activated serine/threonine kinase; FAST; fas-activated serine/threonine kinase; FAST kinase
• Gene ID: 10922
• mRNA Refseq: NM_001258461
• Protein Refseq: NP_001245390
• MIM: 606965
• UniProt ID: Q14296