Recombinant Human Far Upstream Element (FUSE) Binding Protein 1, His-tagged

• Cat.No.: FUBP1-6838H
• Product Overview: Recombinant human FUBP1 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Description: FUBP1 is a protein that in humans is encoded by the FUBP1 gene. This gene encodes a ssDNA binding protein that activates the far upstream element (FUSE) of c-myc and stimulates expression of c-myc in undifferentiated cells. Regulation of FUSE by FUBP occurs through single-strand binding of FUBP to the non-coding strand.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.15M NaCl,1mM DTT.
• Molecular Mass: 20.8kDa(195aa) confirmed by MALDI-TOF
• Protein length: 279-448aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMDVPIP RFAVGIVIGR NGEMIKKIQN DAGVRIQFKP DDGTTPERIA QITGPPDRCQ HAAEIITDLL RSVQAGNPGG PGPGGRGRGR GQGNWNMGPP GGLQEFNFIV PTGKTGLIIG KGGETIKSIS QQSGARIELQ RNPPPNADPN MKLFTIRGTP QQIDYARQLI EEKIG
• Purity: >85% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: FUBP1 far upstream element (FUSE) binding protein 1 [ Homo sapiens ]
• Official Symbol: FUBP1
• Synonyms: FUBP1; far upstream element (FUSE) binding protein 1; FUBP; far upstream element-binding protein 1; FBP; hDH V; DNA helicase V; FUSE-binding protein 1; far upstream element binding protein
• Gene ID: 8880
• mRNA Refseq: NM_003902
• Protein Refseq: NP_003893
• MIM: 603444
• UniProt ID: Q96AE4
• Chromosome Location: 1p31.1
• Function: DNA binding; RNA binding; sequence-specific DNA binding transcription factor activity; single-stranded DNA binding