Recombinant Human FAM3C, FLAG-tagged

• Cat.No.: FAM3C-2150H
• Product Overview: Recombinant Human ILEI (interleukin-like EMT inducer) (aa 25-227) produced inCHOis fused at the C-terminus to a FLAG-tag, ~25kDa.

Specification

• Species: Human
• Source: CHO
• Tag: Flag
• Protein Length: 25-227 a.a.
• Description: ILEI as a key player in both epithelial to mesenchymal transition and late-stage carcinoma progression. EMT is a process that involves changes in gene expression, cytoskeleton organization, cell adhesion, and extracellular matrix composition. This process is important during tissue formation and organogenesis, but also during cancer progression, metastasis and chronic inflammation. ILEI is overexpressed and/or altered in intracellular localization in multiple human tumors, an event strongly correlated to invasion/EMT, metastasis formation, and survival in human colon and breast cancer.
• Concentration: 0.1mg/ml after reconstitution.
• Purity: ≥95% (SDS-PAGE).
• Formulation: Lyophilized. Contains PBS.
• Endotoxin Content: <0.1EU/µg purified protein (LAL test; Bio Whittaker).
• Reconstitution: Reconstitute with 100µl sterile water. Further dilutions should be made with medium containing 5% fetal calf serum or a carrier protein.
• Short Term Storage: +4°C.
• Long Term Storage: -20°C.
• Use/Stability: Stable for at least 6 months after receipt when stored at -20°C.
• Handling: Avoid freeze/thaw cycles. After reconstitution, prepare aliquots and store at -20°C.

Gene Information

• Gene Name: FAM3C family with sequence similarity 3, member C [ Homo sapiens ]
• Synonyms: family with sequence similarity 3, member C; ILEI; GS3786; FAM3C; interleukin-like EMT inducer; predicted osteoblast protein
• Gene ID: 10447
• mRNA Refseq: NM_001040020
• Protein Refseq: NP_001035109
• MIM: 608618
• UniProt ID: Q92520
• Chromosome Location: 7q31
• Function: cytokine activity