Recombinant Human FAM38A, His-tagged

• Cat.No.: FAM38A-12699H
• Product Overview: Recombinant Human FAM38A protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• ProteinLength: 67-373a.a.
• Description: Piezos are large transmembrane proteins conserved among various species, all having between 24 and 36 predicted transmembrane domains. Piezo comes from the Greek piesi, meaning pressure. The FAM38A gene encodes PIEZO1, a protein that induces mechanically activated (MA) currents in various cell types (Coste et al., 2010 [PubMed 20813920]).
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: PIEZO1 piezo-type mechanosensitive ion channel component 1 [ Homo sapiens ]
• Official Symbol: PIEZO1
• Synonyms: PIEZO1; piezo-type mechanosensitive ion channel component 1; FAM38A, family with sequence similarity 38, member A; KIAA0233; protein PIEZO1; family with sequence similarity 38, member A; membrane protein induced by beta-amyloid treatment; Mib; FAM38A
• Gene ID: 9780
• mRNA Refseq: NM_001142864
• Protein Refseq: NP_001136336
• MIM: 611184
• UniProt ID: Q92508
• Chromosome Location: 16q24.3
• Function: ion channel activity