Recombinant Human FAH Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: FAH-3019H
• Product Overview: FAH MS Standard C13 and N15-labeled recombinant protein (NP_000128) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT).
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 46.4 kDa
• AA Sequence: MSFIPVAEDSDFPIHNLPYGVFSTR GDPRPRIGVAIGDQILDLSIIKHLF TGPVLSKHQDVFNQPTLNSFMGLGQ AAWKEARVFLQNLLSVSQARLRDDT ELRKCAFISQASATMHLPATIGDYT DFYSSRQHATNVGIMFRDKENALMP NWLHLPVGYHGRASSVVVSGTPIRR PMGQMKPDDSKPPVYGACKLLDMEL EMAFFVGPGNRLGEPIPISKAHEHI FGMVLMNDWSARDIQKWEYVPLGPF LGKSFGTTVSPWVVPMDALMPFAVP NPKQDPRPLPYLCHDEPYTFDINLS VNLKGEGMSQAATICKSNFKYMYWT MLQQLTHHSVNGCNLRPGDLLASGT ISGPEPENFGSMLELSWKGTKPIDL GNGQTRKFLLDGDEVIITGYCQGDG YRIGFGQCAGKVLPALLPSTRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: FAH fumarylacetoacetate hydrolase [ Homo sapiens (human) ]
• Official Symbol: FAH
• Synonyms: FAH; fumarylacetoacetate hydrolase (fumarylacetoacetase); fumarylacetoacetase; FAA; beta-diketonase; FLJ51912
• Gene ID: 2184
• mRNA Refseq: NM_000137
• Protein Refseq: NP_000128
• MIM: 613871
• UniProt ID: P16930