FAH
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Official Full Name
fumarylacetoacetate hydrolase (fumarylacetoacetase) -
Overview
This gene encodes the last enzyme in the tyrosine catabolism pathway. FAH deficiency is associated with Type 1 hereditary tyrosinemia (HT). -
Synonyms
FAH;fumarylacetoacetate hydrolase (fumarylacetoacetase);fumarylacetoacetase;FAA;beta-diketonase;FLJ51912
Recombinant Proteins
- Zebrafish
- Rhesus macaque
- Rat
- Chicken
- Human
- Mouse
- Mammalian Cell
- HEK293
- Wheat Germ
- HEK293T
- E.coli
- Mammalian cells
- In Vitro Cell Free System
- Mamanlian cells
- His
- GST
- Myc&DDK
- Non
- His&Fc&Avi
- Flag
Involved Pathway
FAH involved in several pathways and played different roles in them. We selected most pathways FAH participated on our site, such as Tyrosine metabolism,Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with FAH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tyrosine metabolism | IL4I1,FAHD1,TPO,MIF,AOX3L1,GOT2B,TYR,GOT2,AOC2,ADH1 |
| Metabolic pathways | KHK,UGT1A7,SYNJ2,SAT1,NADKD1,TH,DOLK,NAMPT,CYP2C8,POLE4 |
Protein Function
FAH has several biochemical functions, for example, fumarylacetoacetase activity,metal ion binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by FAH itself. We selected most functions FAH had, and list some proteins which have the same functions with FAH. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | RNF207,ZDHHC18A,FRRS1,ZNF703,THAP2,ATP2A2A,GM757,NRXN2B,ARAP2,PRICKLE1A |
| protein binding | MLF2,S100A8,GZMA,RUVBL1,MLH3,RAB41,PIR,ALKBH3,YWHAZ,HESX1 |
Interacting Protein
FAH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with FAH here. Most of them are supplied by our site. Hope this information will be useful for your research of FAH.
TCF4;KRTAP5-9;KRTAP10-8;SERTAD1;ADAMTSL4;EGFR
Resources
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References
- Sen, SS; Giri, SS; et al. Immune responses and protection in rohu vaccinated against Aeromonas hydrophila infection. AQUACULTURE INTERNATIONAL 22:1637-1648(2014).
- Ma, T; Chang, GB; et al. Identification of Key Genes in the Response to Salmonella enterica Enteritidis, Salmonella enterica Pullorum, and Poly(I:C) in Chicken Spleen and Caecum. BIOMED RESEARCH INTERNATIONAL :-(2014).
