Recombinant Human FADS2 Protein, His-tagged

• Cat.No.: FADS2-024H
• Product Overview: Recombinant N-terminal His-tagged human FADS2 N-terminal domain (2-131) was purified from E. coli.

Specification

• Description: The protein encoded by this gene is a member of the fatty acid desaturase (FADS) gene family. Desaturase enzymes regulate unsaturation of fatty acids through the introduction of double bonds between defined carbons of the fatty acyl chain. FADS family members are considered fusion products composed of an N-terminal cytochrome b5-like domain and a C-terminal multiple membrane-spanning desaturase portion, both of which are characterized by conserved histidine motifs. This gene is clustered with family members at 11q12-q13.1; this cluster is thought to have arisen evolutionarily from gene duplication based on its similar exon/intron organization. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 16.99 kDa
• Protein length: 2-131
• Purity: ≥95% as determined by SDS-PAGE
• Stability: ≥ 6 months
• Storage: At -80 centigrade.
• Storage Buffer: 50 mM HEPES, pH 8.0, with 150 mM sodium chloride and 10% glycerol

Gene Information

• Gene Name: FADS2 fatty acid desaturase 2 [ Homo sapiens (human) ]
• Official Symbol: FADS2
• Synonyms: FADS2; fatty acid desaturase 2; D6D; DES6; TU13; FADSD6; LLCDL2; SLL0262; acyl-CoA 6-desaturase; delta-6 fatty acid desaturase; delta-6-desaturase; linoleoyl-CoA desaturase (delta-6-desaturase)-like 2; EC 1.14.19.3
• Gene ID: 9415
• mRNA Refseq: NM_004265
• Protein Refseq: NP_004256
• MIM: 606149
• UniProt ID: O95864