Recombinant Human FABP3, His-tagged

• Cat.No.: FABP3-225H
• Product Overview: Recombinant Human FABP3 encoding the human FABP3/HFABP (Val2-Ala133P) with 6 His tag on the N-Terminus was expressed inE.Coli.This protein was purified by Ni-NTA column. MW=17KD.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 2-133 a.a.
• Description: The intracellular fatty acid-binding proteins (FABPs) belong to a multigene family. FABPs are divided into at least three distinct types, namely the hepatic-, intestinal- and cardiac-type. They form 14-15 kDa proteins and are thought to participate in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. They may also be responsible in the modulation of cell growth and proliferation. Fatty acid-binding protein 3 gene contains four exons and its function is to arrest growth of mammary epithelial cells. This gene is a candidate tumor suppressor gene for human breast cancer.
• Sequence: Human FABP3/HFABP (Val²-Ala133P)2VDAFLGTWK LVDSKNFDDY MKSLGVGFAT RQVASMTKPT TIIEKNGDIL TLKTHSTFKN TEISFKLGVE FDETTADDRK VKSIVTLDGG KLVHLQKWDG QETTLVRELI DGKLILTLTH GTAVCTRTYE KEA 133.
• Purity: >95% in SDS gel.
• Formulation: Lyophilized 100μg human FABP3/HFABP in 50 μl of TBS (20 mM Tris, 50mM NaCl, pH8.0). Carry free.
• Application: Cell biology, ELISA.
• Reconstitution: Add 500 μl deionized water to the vial to prepare a working stock solution at 200μg/mL. Allow to set at least 30 minutes at 4°C, mix well.
• Storage: Store lyophilized protein at -20°C or -70°C. Lyophilized protein is stable for up to 6 months from date of receipt at -70°C. Upon reconstitution, this protein can be stored at for a few weeks or at -70°C in a manual defrost freezer for long term storage (six months). Aliquot reconstituted protein to avoid repeated freezing / thawing cycles.

Gene Information

• Gene Name: FABP3 fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) [ Homo sapiens ]
• Synonyms: FABP3; fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor); MDGI; FABP11; H-FABP; O-FABP; Fatty acid-binding protein 3, muscle; mammary-derived growth inhibitor; fatty acid binding protein 11
• Gene ID: 2170
• mRNA Refseq: NM_004102
• Protein Refseq: NP_004093
• MIM: 134651
• UniProt ID: P05413
• Chromosome Location: 1p33-p32
• Pathway: PPAR signaling pathway
• Function: fatty acid binding; icosatetraenoic acid binding; long-chain fatty acid transporter activity; transporter activity