Recombinant Human EZH2 Complex protein, His/GST-tagged

• Cat.No.: EZH2-177H
• Product Overview: Recombinant Human EZH2 Complex protein fused with N-terminal His-GST-tags (EZH2), N-terminal His-tag (SUZ12, RbAP48) was expressed in Insect cells.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST&His
• Protein Length: 2–end (EZH2, RbAp48), 1–end (SUZ12)
• Form: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 16 mM glutathione, 3mM DTT, and 20% glycerol.
• Molecular Mass: 249 kDa (complex)
• Purity: ≥ 80%
• Applications: Useful for Western blot analysis and to investigate protein-protein interactions in the EZH2 complex. Requires EED protein for methyltransferase activity.
• Storage: >6 months at -80 centigrade. Avoid freeze/thaw cycles
• Concentration: 0.51 mg/ml

Gene Information

• Gene Name: EZH2 enhancer of zeste homolog 2 (Drosophila) [ Homo sapiens ]
• Official Symbol: EZH2
• Synonyms: EZH2; enhancer of zeste homolog 2 (Drosophila); enhancer of zeste (Drosophila) homolog 2; histone-lysine N-methyltransferase EZH2; ENX 1; EZH1; KMT6; KMT6A; lysine N-methyltransferase 6; ENX1; WVS2; ENX-1; MGC9169
• Gene ID: 2146
• mRNA Refseq: NM_004456
• Protein Refseq: NP_004447
• MIM: 601573
• UniProt ID: Q15910
• Chromosome Location: 7q35-q36
• Function: DNA binding; histone methyltransferase activity; histone-lysine N-methyltransferase activity; methyltransferase activity; protein binding; transferase activity