Recombinant Human EXOSC5, His-tagged

• Cat.No.: EXOSC5-28337TH
• Product Overview: Recombinant fragment, corresponding to amino acids 6-235 of Human EXOSC5 with an N terminal His tag. MW 29 kDa

Specification

• Description: Exosome component 5, also known as EXOSC5, is a human gene, which is part of the exosome complex.
• Conjugation: HIS
• Source: E. coli
• Form: Lyophilised:Reconstitute with 96 μl distilled water.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: HTDAKIRAENGTGSSPRGPGCSLRHFACEQNLLSRPDGSA SFLQGDTSVLAGVYGPAEVKVSKEIFNKATLEVILRPK IGLPGVAEKSRERLIRNTCEAVVLGTLHPRTSITVVLQ VVSDAGSLLACCLNAACMALVDAGVPMRALFCGVACALDS DGTLVLDPTSKQEKEARAVLTFALDSVERKLLMSSTKG LYSDTELQQCLAAAQAASQHVFRFYRESLQRRYSKS
• Protein length: 6-235 a.a.

Gene Information

• Gene Name: EXOSC5 exosome component 5 [ Homo sapiens ]
• Official Symbol: EXOSC5
• Synonyms: EXOSC5; exosome component 5; exosome complex component RRP46; exosome component Rrp46; hRrp46p; MGC12901; p12B; RRP41B; RRP46; Rrp46p
• Gene ID: 56915
• mRNA Refseq: NM_020158
• Protein Refseq: NP_064543
• MIM: 606492
• Uniprot ID: Q9NQT4
• Chromosome Location: 19q13.1
• Pathway: Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by KSRP, organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Exosome, eukaryotes, organism-specific biosystem
• Function: 3-5-exoribonuclease activity; RNA binding; NOT exoribonuclease activity; protein binding