Recombinant Human EXOSC2, His-tagged

• Cat.No.: EXOSC2-12595H
• Product Overview: Recombinant Human EXOSC2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-293a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: EXOSC2 exosome component 2 [ Homo sapiens ]
• Official Symbol: EXOSC2
• Synonyms: EXOSC2; exosome component 2; exosome complex component RRP4; homolog of yeast RRP4 (ribosomal RNA processing 4); 3 5 exoribonuclease (RRP4); hRrp4p; p7; RRP4; Rrp4p; exosome complex exonuclease RRP4; ribosomal RNA-processing protein 4; homolog of yeast RRP4 (ribosomal RNA processing 4), 3-5-exoribonuclease; homolog of yeast RRP4 (ribosomal RNA processing 4), 3 5 exoribonuclease (RRP4)
• Gene ID: 23404
• mRNA Refseq: NM_014285
• Protein Refseq: NP_055100
• MIM: 602238
• UniProt ID: Q13868
• Chromosome Location: 9q34
• Pathway: Activation of Genes by ATF4, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Destabilization of mRNA by Butyrate Response Factor 1 (BRF1), organism-specific biosystem; Destabilization of mRNA by KSRP, organism-specific biosystem; Destabilization of mRNA by Tristetraprolin (TTP), organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem
• Function: 3-5-exoribonuclease activity; 7S RNA binding; NOT exoribonuclease activity; protein binding