Recombinant Human ESRRB, GST-tagged

• Cat.No.: ESRRB-124H
• Product Overview: Recombinant Human GST-tagged Estrogen-related receptor beta ligand-binding domain (ESRRB-LBD) consists of a 218 a.a. GST tag, a 16 a.a. flexible linker and a 304 a.a. ESRRB-LBD, Acc# AAI31518.1, was expressed in baculovirus-infected insect cells and purified using affinity chromatography.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: Estrogen-related receptor beta (ESRRB, ERRβ, ERR2) is also known as nuclear receptor subfamily 3, group B, member 2 (NR3B2).
• Form: 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 0.5 mM EDTA, 3 mM Dithiothreitol, 7 mM reduced glutathione, 20% glycerol.
• Purity: >80%
• Applications: Ligand binding and coactivator peptide recruitment assays.
• Storage: Immediately store at -80℃. Avoid freeze-thaw cycles.While working, please keep sample on ice.

Gene Information

• Gene Name: ESRRB estrogen-related receptor beta [ Homo sapiens ]
• Official Symbol: ESRRB
• Synonyms: ESRRB; estrogen-related receptor beta; deafness, autosomal recessive 35 , DFNB35, ESRL2; steroid hormone receptor ERR2; ERR2; ERRb; ERRbeta; NR3B2; ERR-beta; ERRbeta-2; ERR beta-2; nuclear receptor ERRB2; orphan nuclear receptor; estrogen receptor-like 2; estrogen-related nuclear receptor beta; nuclear receptor subfamily 3 group B member 2; ESRL2; DFNB35
• Gene ID: 2103
• mRNA Refseq: NM_004452
• Protein Refseq: NP_004443
• MIM: 602167
• UniProt ID: O95718
• Chromosome Location: 14q24.3
• Pathway: Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Wnt Signaling Pathway and Pluripotency, organism-specific biosystem
• Function: RNA polymerase II distal enhancer sequence-specific DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; receptor activity; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; transcription coactivator activity; transcription factor binding; zinc ion binding