Recombinant Human ESR1 Protein

• Cat.No.: ESR1-24H
• Product Overview: Recombinant Human ESR1 full-length protein, without tag, was expressed in insect cell.

Specification

• Species: Human
• Source: Insect Cells
• Tag: Non
• Description: This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014]
• Applications: Nuclear Receptor Assay
• Notes: For Research Use Only. Not for use in diagnostic procedures.
• Storage: One tube of full-length ER Alpha Recombinant Protein. Store at -68 to -85 centigrade.

Gene Information

• Gene Name: ESR1 estrogen receptor 1 [ Homo sapiens (human) ]
• Official Symbol: ESR1
• Synonyms: ESR1; estrogen receptor 1; ER; ESR; ESRA; Era; NR3A1; ESTRR; estrogen receptor; ER-alpha; estradiol receptor; estrogen nuclear receptor alpha; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; nuclear receptor subfamily 3 group A member 1
• Gene ID: 2099
• mRNA Refseq: NM_000125
• Protein Refseq: NP_000116
• MIM: 133430
• UniProt ID: P03372