Recombinant Human ERAP2 Protein, His-tagged

• Cat.No.: ERAP2-483H
• Product Overview: Recombinant Human ERAP2(Pro41~Phe271) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: This gene encodes a zinc metalloaminopeptidase of the M1 protease family that resides in the endoplasmic reticulum and functions in N-terminal trimming antigenic epitopes for presentation by major histocompatibility complex (MHC) class I molecules. Certain mutations in this gene are associated with the inflammatory arthritis syndrome ankylosing spondylitis and pre-eclampsia. This gene is located adjacent to a closely related aminopeptidase gene on chromosome 5.
• Source: E. coli
• Species: Human
• Tag: His
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 30kDa
• Protein length: Pro41~Phe271
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 99%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: ERAP2 endoplasmic reticulum aminopeptidase 2 [ Homo sapiens ]
• Official Symbol: ERAP2
• Synonyms: ERAP2; endoplasmic reticulum aminopeptidase 2; L RAP; leukocyte derived arginine aminopeptidase; LRAP; leukocyte-derived arginine aminopeptidase; L-RAP; FLJ23633; FLJ23701; FLJ23807
• Gene ID: 64167
• mRNA Refseq: NM_001130140
• Protein Refseq: NP_001123612
• MIM: 609497
• UniProt ID: Q6P179