Recombinant Human EPH Receptor A8, His-tagged

• Cat.No.: EPHA8-2145H
• Product Overview: Recombinant human Receptor Ephrin A8 extracellular domain (C-terminus fused with 6xHis)produced inmammalian cellscontains 521 amino acids with predicted MW 57.66 KD, and 21cysteines. It also has 3 N-link glycosylation sites with MW increase up to 15 KD.

Specification

• Species: Human
• Source: Mammalian Cells
• Tag: His
• Description: Human receptor Ephrin A8 (Ephrin type A receptor 8) functions as a receptor for ephrin A2,A3 and A5. Its extracellular domain contains a cysteine domain and 2 fibronectin type III repeats. It plays a role in development of the mammalian nervous system.
• Purity: >90%.
• Recommended Storage Temperature: -70 °C.

Gene Information

• Gene Name: EPHA8 EPH receptor A8 [ Homo sapiens ]
• Synonyms: EPH receptor A8; EEK; EK3; HEK3; KIAA1459; EPHA8; ephrin type-A receptor 8; EPH-like kinase 3; tyrosylprotein kinase; protein-tyrosine kinase; hydroxyaryl-protein kinase; EPH- and ELK-related kinase; EPH- and ELK-related tyrosine kinase; tyrosine-protein kinase receptor EEK; Tyrosine-protein kinase receptor EEK;EphA8; Hek3; ephrin receptorEphA8; EC 2.7.10.1
• Gene ID: 2046
• mRNA Refseq: NM_001006943
• Protein Refseq: NP_001006944
• MIM: 176945
• UniProt ID: P29322s
• Chromosome Location: 1p36.12
• Pathway: Axon guidance
• Function: ATP binding; ephrin receptor activity; nucleotide binding; protein binding; receptor activity; signal transducer activity; transferase activity