Recombinant Human EPH Receptor A5, GST-tagged

• Cat.No.: EPHA5-696H
• Product Overview: Recombinant human EPH receptor A5 catalytic domain (aa 595-1037) with GST tag is expressed inInsect cells.Activated in vitro via auto-phosphorylation.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Protein Length: 595-1037 a.a.
• Description: EPH receptor A5 (ephrin type-A receptor 5) is a protein that in humans is encoded by the EPHA5 gene. This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin recepors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands.
• Concentration: 0.46 mg/ml.
• Formulation: Liquid in 50 mM Tris, pH 7.5 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2mM DTT + 50% glycerol.
• Specific Activity: 1290 nmole of phosphate transferred to poly [Glu,Tyr] 4:1 substrate per minute per mg of total protein at 30°C. Activity determined at a final protein concentration of 1 μg/ml.
• Storage: Stable for 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: EPHA5 EPH receptor A5 [ Homo sapiens ]
• Synonyms:
  EPHA5; EPH receptor A5; EHK-1; EK7; EPH homology kinase 1; EPH-like kinase 7; Eph homology kinase-1; OTTHUMP00000223029; ephrin type-A receptor 5; receptor protein-tyrosine kinase HEK7; tyrosine-protein kinase receptor EHK-1; CEK7; EHK1; HEK7; TYRO4; EC 2.7.10.1
• Gene ID: 2044
• mRNA Refseq: NM_004439
• Protein Refseq: NP_004430
• MIM: 600004
• UniProt ID: P54756
• Chromosome Location: 4q13.1
• Pathway: xon guidance
• Function: ATP binding; nucleotide binding; protein binding; receptor activity; transferase activity; transmembrane-ephrin receptor activity