Recombinant Human EPH Receptor A3, GST-tagged, Active

• Cat.No.: EPHA3-301H
• Product Overview: Recombinant human EPHA3 (571-end) was expressed by baculovirus inSf9 insect cellsusing an N-terminal GST tag. MW=72kDa.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Protein Length: 571-end a.a.
• Description: EPHA3 is a member of the ephrin receptor subfamily of protein-tyrosine kinases that bind the ephrin-A ligand and have diverse cellular function. Analysis of human colorectal, breast, lung and pancreatic cancer samples shows somatic mutations in the EPHA3 gene. EPHA3 gene expression can be regulated by CD28 and IGF-1 in Jurkat cells and expression of EPHA3 is associated with adherence and motility of malignant T cells.
• Sequence: 571-end.
• Applications: Kinase Assay, Western Blot.
• Storage And Stability: Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: EPHA3 EPH receptor A3 [ Homo sapiens ]
• Synonyms: EPHA3; EPH receptor A3; ETK; HEK; ETK1; HEK4; TYRO4; ephrin receptor EphA3; human embryo kinase 1; eph-like tyrosine kinase 1; TYRO4 protein tyrosine kinase; EC 2.7.10.1
• Gene ID: 2042
• mRNA Refseq: NM_005233
• Protein Refseq: NP_005224
• MIM: 179611
• UniProt ID: P29320
• Chromosome Location: 3p11
• Pathway: Axon guidance
• Function: ATP binding; ephrin receptor activity; nucleotide binding; protein binding; receptor activity; transferase activity