Recombinant Human ENPP1 protein, Myc/DDK-tagged

• Cat.No.: ENPP1-3365H
• Product Overview: Recombinant Human ENPP1 protein, fused to Myc/DDK-tag at C-terminus, was expressed in human 293 cells (HEK293).

Specification

• Description: This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Molecular Mass: 99.8 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 μg/mL as determined by microplate BCA method

Gene Information

• Gene Name: ENPP1
• Official Symbol: ENPP1
• Synonyms: M6S1; NPP1; NPPS; PC-1; PCA1; ARHR2; COLED; PDNP1
• Gene ID: 5167
• mRNA Refseq: NM_006208.3
• Protein Refseq: NP_006199.2
• MIM: 173335
• UniProt ID: P22413