Recombinant Human EN2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: EN2-518H
• Product Overview: EN2 MS Standard C13 and N15-labeled recombinant protein (NP_001418) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 34 kDa
• AA Sequence: MEENDPKPGEAAAAVEGQRQPESSPGGGSGGGGGSSPGEADTGRRRALMLPAVLQAPGNHQHPHRITNFFIDNILRPEFGRRKDAGTCCAGAGGGRGGGAGGEGGASGAEGGGGAGGSEQLLGSGSREPRQNPPCAPGAGGPLPAAGSDSPGDGEGGSKTLSLHGGAKKGGDPGGPLDGSLKARGLGGGDLSVSSDSDSSQAGANLGAQPMLWPAWVYCTRYSDRPSSGPRSRKPKKKNPNKEDKRPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKKATGNKNTLAVHLMAQGLYNHSTTAKEGKSDSETRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: EN2 engrailed homeobox 2 [ Homo sapiens (human) ]
• Official Symbol: EN2
• Synonyms: EN2; engrailed homeobox 2; homeobox protein engrailed-2; hu-En-2; engrailed-2; engrailed homolog 2; homeobox protein en-2
• Gene ID: 2020
• mRNA Refseq: NM_001427
• Protein Refseq: NP_001418
• MIM: 131310
• UniProt ID: P19622