Recombinant Human EN2 Protein, His-tagged

• Cat.No.: EN2-1424H
• Product Overview: Recombinant Human EN2 Protein (His64-Arg246) with N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: His64-Arg246
• Description: Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 23.7 kDa
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: EN2 engrailed homeobox 2 [ Homo sapiens (human) ]
• Official Symbol: EN2
• Synonyms: EN2; engrailed homeobox 2; homeobox protein engrailed-2; hu-En-2; engrailed-2; engrailed homolog 2; homeobox protein en-2
• Gene ID: 2020
• mRNA Refseq: NM_001427
• Protein Refseq: NP_001418
• MIM: 131310
• UniProt ID: P19622