Recombinant Human EME2 Protein, GST-tagged

• Cat.No.: EME2-3276H
• Product Overview: Human EME2 full-length ORF ( AAI67808.1, 1 a.a. - 444 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Species: Human
• Source: Wheat Germ
• Tag: GST
• Description: EME2 forms a heterodimer with MUS81 (MIM 606591) that functions as an XPF (MIM 278760)-type flap/fork endonuclease in DNA repair (Ciccia et al., 2007 [PubMed 17289582]).[supplied by OMIM, Mar 2008]
• Molecular Mass: 48.9 kDa
• AA Sequence: MARVGPGRAGVSCQGRGRGRGGSGQRRPPTWEISDSDAEDSAGSEAAARARDPAGERRAAAEALRLLRPEQVLKRLAVCVDTAILEDAGADVLMEALEALGCECRIEPQRPARSLRWTRASPDPCPRSLPPEVWAAGEQELLLLLEPEEFLQGVATLTQISGPTHWVPWISPETTARPHLAVIGLDAYLWYRSLSCPQQGWLGRGFRGGGLWQRPSSGRAGPMGSGEEWSPLLRSRQHVSRGTQQPESPKVAGAEVAVSWPEVEEVRACLSWALVLLQLWANLDVLLVASWQELSRHVCAVTKALAQYPLKCVMPRLKGGRITSRQYRESQAFSFCTAGRWAAGEPVARDGAGLQAAWRRQIRQFSRVSPAVADAVVTAFPSPRLLQQALEACSTERERMGLLADLPVPPSEGGRPRRVGPDLSRRICLFLTTANPDLLLDLGS
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: EME2 essential meiotic structure-specific endonuclease subunit 2 [ Homo sapiens (human) ]
• Official Symbol: EME2
• Synonyms: EME2; essential meiotic structure-specific endonuclease subunit 2; Essential Meiotic Structure-Specific Endonuclease Subunit 2; SLX2 Structure-Specific Endonuclease Subunit Homolog B (S. Cerevisiae); SLX2 Structure-Specific Endonuclease Subunit Homolog B; Essential Meiotic Endonuclease 1 Homolog 2 (S. Pombe); Probable Crossover Junction Endonuclease EME2; Essential Meiotic Endonuclease 1 Homolog 2; Homolog Of Yeast EME1 Endonuclease 2; EC 3.1.22.-; SLX2B; Gs125; probable crossover junction endonuclease EME2; SLX2 structure-specific endonuclease subunit homolog B; essential meiotic endonuclease 1 homolog 2; homolog of yeast EME1 endonuclease 2
• Gene ID: 197342
• mRNA Refseq: NM_001257370
• Protein Refseq: NP_001244299
• MIM: 610886
• UniProt ID: A4GXA9