EME2
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Official Full Name
essential meiotic endonuclease 1 homolog 2 (S. pombe) -
Synonyms
2810013J18Rik
Recombinant Proteins
- Human
- Mouse
- Mammalian Cells
- Wheat Germ
- HEK293
- In Vitro Cell Free System
- His
- GST
- Avi
- Fc
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| EME2-1020H | Recombinant Human EME2 | Mammalian Cells | Human | His |
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| EME2-3276H | Recombinant Human EME2 Protein, GST-tagged | Wheat Germ | Human | GST |
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| EME2-5172M | Recombinant Mouse EME2 Protein | Mammalian Cells | Mouse | His |
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| EME2-2769M | Recombinant Mouse EME2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | Avi&Fc&His |
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| EME2-2769M-B | Recombinant Mouse EME2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| EME2-2848H | Recombinant Human EME2 Protein, His (Fc)-Avi-tagged | HEK293 | Human | Avi&Fc&His |
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| EME2-2848H-B | Recombinant Human EME2 Protein Pre-coupled Magnetic Beads | HEK293 | Human |
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| EME2-4241HF | Recombinant Full Length Human EME2 Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 444 amino acids |
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Involved Pathway
EME2 involved in several pathways and played different roles in them. We selected most pathways EME2 participated on our site, such as DNA Double-Strand Break Repair,DNA Repair,Fanconi Anemia Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with EME2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Resolution of D-Loop Structures | RTEL1,GEN1,RAD51AP1,KIAA0146 |
| Homology Directed Repair | PPP4CB,PPP4CA,TIMELESS,PPP4R2,RHNO1,RTEL1,PPP4R2B,PPP4R2A,RNF4,KIAA0146 |
| DNA Repair | GPS1,RAD9A,POLI,TIMELESS,CHEK1,PAXIP1,PARP2,DCLRE1A,TDP1,PNKP |
| Fanconi Anemia Pathway | MLH1,SLX4,ATRIP,RPA1,FANCF,HES1,TOP3B,RPA4,MUS81,FANCL |
| HDR through Homologous Recombination (HR) or Single Strand Annealing (SSA) | TP53BP1,RBBP8,TOPBP1,BRE,RAD51AP1,WRN,HUS1,GEN1,KIAA0146,EME1 |
| HDR through Homologous Recombination (HRR) | WRN,EME1,TOPBP1,FUZ,RHNO1,RAD9B,RBBP8,HUS1,RAD9,RTEL1 |
| DNA Double-Strand Break Repair | RTEL1,PARP1,BAZ1B,TP53BP1,RIF1,THRSP,RAD51AP1,SMARCA5,PPP4CB,TIPIN |
Protein Function
EME2 has several biochemical functions, for example, DNA binding,endonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EME2 itself. We selected most functions EME2 had, and list some proteins which have the same functions with EME2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| endonuclease activity | DROSHA,EAR3,ZC3H12A,EME1,EXOG,DNASE2A,RNASE7,SETMAR,RNASE2,RNASEL2 |
| DNA binding | RABGEF1L,SSH1,KRBA2,ZBTB12,SP8,ZNF571,PPARDB,DMBX1,FANCI,MAPK1 |
Interacting Protein
EME2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EME2 here. Most of them are supplied by our site. Hope this information will be useful for your research of EME2.
FEN1
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References
- Pepe, A; West, SC; et al. MUS81-EME2 Promotes Replication Fork Restart. CELL REPORTS 7:1048-1055(2014).
- Pepe, A; West, SC; et al. Substrate specificity of the MUS81-EME2 structure selective endonuclease. NUCLEIC ACIDS RESEARCH 42:3833-3845(2014).
