Recombinant Human ELP5, His-tagged

• Cat.No.: ELP5-15918H
• Product Overview: Recombinant human ELP5 protein, fused to His tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: Elongator acetyltransferase complex subunit 5, also known as ELP5, acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. This protein is involved in cell migration.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
• Molecular Mass: 37.2 kDa (339aa) confirmed by MALDI-TOF
• Protein length: 1-316aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMTPSEGA RAGTGRELEM LDSLLALGGL VLLRDSVEWE GRSLLKALVK KSALCGEQVH ILGCEVSEEE FREGFDSDIN NRLVYHDFFR DPLNWSKTEE AFPGGPLGAL RAMCKRTDPV PVTIALDSLS WLLLRLPCTT LCQVLHAVSH QDSCPGDSSS VGKVSVLGLL HEELHGPGPV GALSSLAQTE VTLGGTMGQA SAHILCRRPR QRPTDQTQWF SILPDFSLDL QEGPSVESQP YSDPHIPPVD PTTHLTFNLH LSKKEREARD SLILPFQFSS EKQQALLRPR PGQATSHIFY EPDAYDDLDQ EDPDDDLDI
• Purity: >80% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term. For long term storage, aliquot and store at at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: ELP5 elongator acetyltransferase complex subunit 5 [ Homo sapiens (human) ]
• Official Symbol: ELP5
• Synonyms: ELP5; elongator acetyltransferase complex subunit 5; DERP6; MST071; HSPC002; MSTP071; C17orf81; S-phase 2 protein; dermal papilla derived protein 6; dermal papilla-derived protein 6
• Gene ID: 23587
• mRNA Refseq: NM_015362
• Protein Refseq: NP_056177
• MIM: 615019
• UniProt ID: Q8TE02
• Chromosome Location: 17p13.1
• Function: protein binding