Recombinant Human ELAVL3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ELAVL3-4985H
• Product Overview: ELAVL3 MS Standard C13 and N15-labeled recombinant protein (NP_001411) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 39.4 kDa
• AA Sequence: MVTQILGAMESQVGGGPAGPALPNG PLLGTNGATDDSKTNLIVNYLPQNM TQDEFKSLFGSIGDIESCKLVRDKI TGQSLGYGFVNYSDPNDADKAINTL NGLKLQTKTIKVSYARPSSASIRDA NLYVSGLPKTMSQKEMEQLFSQYGR IITSRILVDQVTGVSRGVGFIRFDK RIEAEEAIKGLNGQKPLGAAEPITV KFANNPSQKTGQALLTHLYQSSARR YAGPLHHQTQRFRLDNLLNMAYGVK SPLSLIARFSPIAIDGMSGLAGVGL SGGAAGAGWCIFVYNLSPEADESVL WQLFGPFGAVTNVKVIRDFTTNKCK GFGFVTMTNYDEAAMAIASLNGYRL GERVLQVSFKTSKQHKATRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ELAVL3 ELAV like RNA binding protein 3 [ Homo sapiens (human) ]
• Official Symbol: ELAVL3
• Synonyms: ELAVL3; ELAV like RNA binding protein 3; HUC; HUCL; PLE21; ELAV-like protein 3; ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C); ELAV like neuron-specific RNA binding protein 3; Hu antigen C; hu-antigen C; paraneoplastic cerebellar degeneration-associated antigen; paraneoplastic limbic encephalitis antigen 21
• Gene ID: 1995
• mRNA Refseq: NM_001420
• Protein Refseq: NP_001411
• MIM: 603458
• UniProt ID: Q14576