Recombinant Human ELAC1, His-tagged

• Cat.No.: ELAC1-96H
• Product Overview: Recombinant human ELAC1 was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: ELAC1 also known as Zinc phosphodiesterase ELAC protein 1. Zinc phosphodiesterase, which displays some tRNA 3"-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3"-trailer from precursor tRNA.
• Source: E.coli
• Species: Human
• Tag: His
• Form: Liquid. In Phosphate buffered saline (pH7.4) containing 10% glycerol, 1mM DTT
• Molecular Mass: 42.4 kDa (386aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSMDVTF LGTGAAYPSP TRGASAVVLR CEGECWLFDC GEGTQTQLMK SQLKAGRITK IFITHLHGDH FFGLPGLLCT ISLQSGSMVS KQPIEIYGPV GLRDFIWRTM ELSHTELVFH YVVHELVPTA DQCPAEELKE FAHVNRADSP PKEEQGRTIL LDSEENSYLL FDDEQFVVKA FRLFHRIPSF GFSVVEKKRP GKLNAQKLKD LGVPPGPAYG KLKNGISVVL ENGVTISPQD VLKKPIVGRK ICILGDCSGV VGDGGVKLCF EADLLIHEAT LDDAQMDKAK EHGHSTPQMA ATFAKLCRAK RLVLTHFSQR YKPVALAREG ETDGIAELKK QAESVLDLQE VTLAEDFMVI SIPIKK
• Purity: >80% by SDS - PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: ELAC1 elaC homolog 1 (E. coli) [ Homo sapiens ]
• Official Symbol: ELAC1
• Synonyms: ELAC1; elaC homolog 1 (E. coli); elaC (E. coli) homolog 1; zinc phosphodiesterase ELAC protein 1; D29; tRNA Z (short form); RNase Z 1; tRNase ZS; tRNase Z 1; deleted in Ma29; ribonuclease Z 1; tRNA 3 endonuclease 1; elaC homolog protein 1; tRNA 3 processing endoribonuclease; FLJ59261
• Gene ID: 55520
• mRNA Refseq: NM_018696
• Protein Refseq: NP_061166
• MIM: 608079
• UniProt ID: Q9H777
• Chromosome Location: 18q21
• Pathway: RNA transport, organism-specific biosystem; RNA transport, conserved biosystem
• Function: endonuclease activity; endoribonuclease activity, producing 5-phosphomonoesters; hydrolase activity; metal ion binding