Recombinant Human EIF4B
| Cat.No. : | EIF4B-27411TH |
| Product Overview : | Recombinant full length Human eIF4B with a N terminal proprietary tag: predicted molecular weight 93.28 kDa inclusive of tag. |
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| Description : | eIF4B is required for the binding of mRNA to ribosomes. It functions in close association with eIF4F and eIF4A. It binds near the 5-terminal cap of mRNA in the presence of eIF4F and ATP. |
| Protein length : | 611 amino acids |
| Molecular Weight : | 93.280kDa inclusive of tags |
| Source : | Wheat germ |
| Form : | Liquid |
| Purity : | Proprietary Purification |
| Storage buffer : | pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl |
| Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
| Sequences of amino acids : | MAASAKKKNKKGKTISLTDFLAEDGGTGGGSTYVSKPVSW ADETDDLEGDVSTTWHSNDDDVYRAPPIDRSILPTAPRAA REPNIDRSRLPKSPPYTAFLGNLPYDVTEESIKEFFRGLN ISAVRLPREPSNPERLKGFGYAEFEDLDSLLSALSLNEES LGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKTDTDWR ARPATDSFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDG YRDGPCRDMDRYGGRDRYDDRGSRDYDRGYDSRIGSGRRA FGSGYRRDDDYRGGGDRYEDRYDRRDDRSWSSRDDYSRDD YRRDDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASI FGGAKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRP RERHPSWRSEETQERERSRTGSESSQTGTSTTSSRNARRR ESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPAPPPK ENAWVKRSSNPPARSQSSDTEQQSPTSGGGKVAPAQPSEE GPGRKDENKVDGMNAPKGQTGNSSRGPGDGGNRDHWKESD RKDGKKDQDSRSAPEPKKPEENPASKFSSASKYAALSVDG EDENEGEDYAE |
| Tag : | Non |
| Gene Name | EIF4B eukaryotic translation initiation factor 4B [ Homo sapiens ] |
| Official Symbol | EIF4B |
| Synonyms | EIF4B; eukaryotic translation initiation factor 4B; |
| Gene ID | 1975 |
| mRNA Refseq | NM_001417 |
| Protein Refseq | NP_001408 |
| MIM | 603928 |
| Uniprot ID | P23588 |
| Chromosome Location | 12q13.13 |
| Pathway | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Deadenylation of mRNA, organism-specific biosystem; Deadenylation-dependent mRNA decay, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; |
| Function | RNA binding; nucleotide binding; translation initiation factor activity; |
Not For Human Consumption!
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