Recombinant Human EIF2A, His-tagged

• Cat.No.: EIF2A-28490TH
• Product Overview: Recombinant full length Human eIF2S1 with N terminal His tag; MWt 38.2kDa ,

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 315 amino acids
• Description: EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes (Zoll et al.
• Conjugation: HIS
• Molecular Weight: 38.200kDa inclusive of tags
• Tissue specificity: Widely expressed. Expressed at higher level in pancreas, heart, brain and placenta.
• Form: Liquid
• Storage buffer: Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MPGLSCRFYQ HKFPEVEDVV MVNVRSIAEM GAYVSLLEYN NIEGMILLSE LSRRRIRSIN KLIRIGRNEC VVVIRVDKEK GYIDLSKRRV SPEEAIKCED KFTKSKTVYS ILRHVAEVLE YTKDEQLESL FQRTAWVFDD KYKRPGYGAY DAFKHAVSDP SILDSLDLNE DEREVLINNI NRRLTPQAVK IRADIEVACY GYEGIDAVKE ALRAGLNCST ENMPIKINLI APPRYVMTTT TLERTEGLSV LSQAMAVIKE KIEEKRGVFN VQMEPKVVTD TDETELARQM ERLERENAEV DGDDDAEEME AKAED
• Sequence Similarities: Belongs to the WD repeat EIF2A family.Contains 3 WD repeats.

Gene Information

• Gene Name: EIF2A eukaryotic translation initiation factor 2A, 65kDa [ Homo sapiens ]
• Official Symbol: EIF2A
• Synonyms: EIF2A; eukaryotic translation initiation factor 2A, 65kDa; eukaryotic translation initiation factor 2A; EIF 2A
• Gene ID: 83939
• mRNA Refseq: NM_032025
• Protein Refseq: NP_114414
• MIM: 609234
• Uniprot ID: Q9BY44
• Chromosome Location: 3q25.1
• Pathway: IL-6 Signaling Pathway, organism-specific biosystem; TGF-beta receptor signaling, organism-specific biosystem
• Function: ribosome binding; tRNA binding; translation initiation factor activity