Recombinant Human EIF1AY, His-tagged

• Cat.No.: EIF1AY-3418H
• Product Overview: Recombinant human EIF1AY protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Cat. No.: EIF1AY-3418H
• Description: EIF1AY is similar to eukaryotic translation initiation factor 1A (EIF1A). This protein seems to be required for maximal rate of protein biosynthesis. It enhances ribosome dissociation into subunits and is required for the binding of the 43S complex (a 40S subunit, eIF2/GTP/Met-tRNAi and eIF3) to the 5" end of capped RNA.
• Source: E.coli.
• Form: Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 1 mM DTT, 100 mM NaCl, 20% Glycerol.
• Molecular Weight: 18.8 kDa (167aa) confirmed by MALDI-TOF.
• Purity: > 95% by SDS - PAGE.
• Concentration: 0.5 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MGSSHHHHHH SSGLVPRGSH MGSMPKNKGK GGKNRRRGKN ENESEKRELV FK E DGQEYAQ VIKMLGNGRL EALCFDGVKR LCHIRGKLRKKVWINTSDII LVG LR D YQDN KADVILKYNA DEARSLKAYG ELPEHAKINE TDTFGPGDDD EIQFDDIGDD D EDIDDI.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: RNA transport

Gene Information

• Gene Name: EIF1AY eukaryotic translation initiation factor 1A, Y-linked [ Homo sapiens ]
• Synonyms: eukaryotic translation initiation factor 1A, Y-linked; EIF1AY; eukaryotic translation initiation factor 1A, Y-chromosomal; eIF-4C; eIF-1A Y isoform; eukaryotic translation initiation factor 4C; eukaryotic translation initiation factor 1A, Y chromosome; Eukaryotic translation initiation factor 4C
• Gene ID: 9086
• mRNA Refseq: NM_004681
• Protein Refseq: NP_004672
• MIM: 400014
• UniProt ID: O14602
• Chromosome Location: Yq11.223
• Function: RNA binding; protein binding; translation initiation factor activity