Recombinant Human EDC3, GST-tagged

• Cat.No.: EDC3-12276H
• Product Overview: Recombinant Human EDC3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its degradation from the 5-prime end (Fenger-Gron et al., 2005 [PubMed 16364915]).
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 158-508a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: EDC3 enhancer of mRNA decapping 3 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: EDC3
• Synonyms: EDC3; enhancer of mRNA decapping 3 homolog (S. cerevisiae); LSM16, LSM16 homolog (EDC3, S. cerevisiae) , YJDC, yjeF domain containing (E.coli); enhancer of mRNA-decapping protein 3; FLJ21128; hYjeF_N2 15q23; YJEFN2; yjeF_N2; hYjeF_N2; hYjeF_N2-15q23; yjeF domain containing; yjeF domain-containing protein 1; LSM16 homolog (EDC3, S. cerevisiae); yjeF N-terminal domain-containing protein 2; YJDC; LSM16; FLJ31777
• Gene ID: 80153
• mRNA Refseq: NM_001142443
• Protein Refseq: NP_001135915
• MIM: 609842
• UniProt ID: Q96F86
• Chromosome Location: 15q24.1
• Pathway: Deadenylation-dependent mRNA decay, organism-specific biosystem; Decapping complex, organism-specific biosystem; Decapping complex, conserved biosystem; Gene Expression, organism-specific biosystem; RNA degradation, organism-specific biosystem; RNA degradation, conserved biosystem; mRNA Decay by 5 to 3 Exoribonuclease, organism-specific biosystem
• Function: RNA binding; identical protein binding; protein binding