EDC3
-
Official Full Name
enhancer of mRNA decapping 3 homolog (S. cerevisiae) -
Overview
EDC3 is associated with an mRNA-decapping complex required for removal of the 5-prime cap from mRNA prior to its;degradation from the 5-prime end (Fenger-Gron et al., 2005 (PubMed 16364915)). -
Synonyms
EDC3;enhancer of mRNA decapping 3 homolog (S. cerevisiae);LSM16, LSM16 homolog (EDC3, S. cerevisiae) , YJDC, yjeF domain containing (E.coli);enhancer of mRNA-decapping protein 3;FLJ21128;hYjeF_N2 15q23;YJEFN2;EDC 3;Enhancer of mRNA decapping 3 homolog;Enhancer of mRNA decapping protein 3;FLJ31777;LSM 16;LSM16;LSM16 homolog (EDC3 S. cerevisiae);LSM16 homolog;YJDC;YjeF domain containing;YjeF domain containing protein 1;yjeF_N2;hYjeF_N2;hYjeF_N2-15q23;OTTHUMP00000183472;yjeF domain-containing protein 1;LSM16 homolog (EDC3, S. cerevisiae);yjeF N-terminal domain-containing protein 2
Recombinant Proteins
- Human
- Rhesus macaque
- Chicken
- Zebrafish
- Mouse
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- Wheat Germ
- In Vitro Cell Free System
- Mammalian cells
- GST
- His
- Non
- His&Fc&Avi
- Myc&DDK
- Flag
Involved Pathway
EDC3 involved in several pathways and played different roles in them. We selected most pathways EDC3 participated on our site, such as RNA degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with EDC3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| RNA degradation | C1D,SMX5,CNOT6,PABPC1,MPHOSPH6,ENO1,NUDT16,CNOT8,CNOT10,CNOT3B |
Protein Function
EDC3 has several biochemical functions, for example, identical protein binding,mRNA binding,phosphodiesterase decapping endonuclease activity. Some of the functions are cooperated with other proteins, some of the functions could acted by EDC3 itself. We selected most functions EDC3 had, and list some proteins which have the same functions with EDC3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | COMMD7,LEPR,NUAK1,IFT20,INTS9,COPS7B,IYD,SH2D3A,APITD1,MDFI |
| identical protein binding | APOE,FGFR1,PYCARD,RB1,BNIP2,ZDHHC17,CCL3,KRTAP10-5,TNPO3,ALDH4A1 |
| mRNA binding | DOM3Z,TDRD7,RBM5,THOC2,ADARB1,LIN28A,RBMY1A1,CSTF2T,TPR,NOVA1 |
Interacting Protein
EDC3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EDC3 here. Most of them are supplied by our site. Hope this information will be useful for your research of EDC3.
DCP1B;DCP1A;DDX6;YWHAB
Resources
Related Services
Related Products
References
- Jung, JH; Kim, J; et al. Roles of Edc3 in the oxidative stress response and CaMCA1-encoded metacaspase expression in Candida albicans. FEBS JOURNAL 281:4841-4851(2014).
- Kim, EC; Kim, J; et al. Deletion analysis of LSm, FDF, and YjeF domains of Candida albicans Edc3 in hyphal growth and oxidative-stress response. JOURNAL OF MICROBIOLOGY 53:111-115(2015).
