Recombinant Human ECE1 protein, His & T7-tagged

• Cat.No.: ECE1-2687H
• Product Overview: Recombinant Human ECE1 aa. (Leu469~Glu721 (Accession # P42892)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: Leu469~Glu721
• Description: The protein encoded by this gene is involved in proteolytic processing of endothelin precursors to biologically active peptides. Mutations in this gene are associated with Hirschsprung disease, cardiac defects and autonomic dysfunction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 32.8kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >95%
• Characteristic: The isoelectric point is 6.8.
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.

Gene Information

• Gene Name: ECE1 endothelin converting enzyme 1 [ Homo sapiens (human) ]
• Official Symbol: ECE1
• Synonyms: ECE; endothelin-converting enzyme 1; ECE-1
• Gene ID: 1889
• mRNA Refseq: NM_001113347.1
• Protein Refseq: NP_001106818.1
• UniProt ID: P42892