Recombinant Human Early Growth Response 4

• Cat.No.: EGR4-2084H
• Product Overview: Recombinant Human Early Growth Response 4 is produced inSf9 Cells.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: Non
• Description: The recombinant EGR-4 protein can be employed in the following fields of research: a) Promoter studies: Identification of EGR-4 binding promoter elements. b) Detection of EGR-4 interacting proteins. c) Signal transduction: Assay for the effect on the nuclear component EGR-4. d) Screening for EGR-4 activity in tumor cells and lines. e) Drug screening: Effect on EGR-4 generation and DNA binding.
• Purity: ≥95% (SDS-PAGE).
• Formulation: Liquid. In 20mM HEPES, pH 7.9, containing 25% glycerol, 420mM sodium chloride, 0.2mM EDTA and 1.5mM magnesium chloride.
• Specificity: Binds specifically to an oligonucleotide with the sequence GCG GGG GCG.
• Application: EMSA promoter characterization, in vitro transcription assay, analysis of nuclear extracts (oligonucleotides and recombinant protein serve as positive control).
• Storage: -80°C. Avoid freeze/thaw cycles.

Gene Information

• Gene Name: EGR4 early growth response 4 [ Homo sapiens ]
• Synonyms: EGR4; early growth response 4; NGFIC; NGFI-C; PAT133; AT133; EGR-4
• Gene ID: 1961
• mRNA Refseq: NM_001965
• Protein Refseq: NP_001956
• MIM: 128992
• UniProt ID: Q05215
• Chromosome Location: 2p13
• Function: metal ion binding; transcription activator activity; transcription factor activity; zinc ion binding