Recombinant Human E2F2 cell lysate
Cat.No. : | E2F2-520HCL |
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Species : | Human |
Tag : | Non |
Description : | The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. |
Size : | 100 ul |
Storage Buffer : | 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue) |
Applications : | Western Blot; |
Gene Name | E2F2 E2F transcription factor 2 [ Homo sapiens ] |
Official Symbol | E2F2 |
Synonyms | E2F2; E2F transcription factor 2; transcription factor E2F2; E2F 2; E2F-2; |
Gene ID | 1870 |
mRNA Refseq | NM_004091 |
Protein Refseq | NP_004082 |
MIM | 600426 |
UniProt ID | Q14209 |
Chromosome Location | 1p36 |
Pathway | Assembly of the pre-replicative complex, organism-specific biosystem; Association of licensing factors with the pre-replicative complex, organism-specific biosystem; Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; CDC6 association with the ORC:origin complex, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; |
Function | DNA binding; core promoter binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription factor binding; |
◆ Recombinant Proteins | ||
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E2F2-2017H | Recombinant Human E2F2 Protein (Arg129-Tyr429), N-His tagged | +Inquiry |
E2F2-2595M | Recombinant Mouse E2F2 Protein, His (Fc)-Avi-tagged | +Inquiry |
E2F2-1635H | Recombinant Human E2F2 protein, His & GST-tagged | +Inquiry |
E2F2-4931M | Recombinant Mouse E2F2 Protein | +Inquiry |
◆ Cell & Tissue Lysates | ||
E2F2-520HCL | Recombinant Human E2F2 cell lysate | +Inquiry |
Not For Human Consumption!
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