Recombinant Human Dynein, Light chain, Tctex-Type 1, His-tagged

• Cat.No.: DYNLT1-3518H
• Product Overview: Recombinant human DYNLT1 protein, fused to His-tag at N-terminus, was expressed inE.coliand purified by using conventional chromatography techniques(1-113aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Dynein light chain Tctex-type 1, also known as DYNLT1, belongs to the dynein light chain Tctex-type family. DYNLT1 acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein is the major motor protein complex responsible for minus-end, microtubule-based motile processes. Each dynein complex consists of 2 heavy chains that have ATPase and motor activities, plus a group of accessory polypeptides. DYNLT1 is a dynein light chain involved in cargo binding.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT,30% glycerol, 0.1M NaCl
• Molecular Weight: 14.6 kDa (133aa), confirmed by MALDI-TOF
• Purity: > 95% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay )
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MEDYQAAEET AFVVDEVSNI VKEAIESAIG GNAYQHSKVN QWTTNVVEQT LSQLTKLGKP FKYIVTCVIMQKNGAGLHTA SSCFWDSSTD GSCTVRWENK TMYCIVSAFG LSI
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: DYNLT1 dynein, light chain, Tctex-type 1 [ Homo sapiens]
• Synonyms: DYNLT1; CW-1; TCTEL1; tctex-1; MGC111571; dynein light chain Tctex-type 1; T-complex testis-specific protein 1 homolog; t-complex-associated-testis-expressed 1-like 1
• Gene ID: 6993
• mRNA Refseq: NM_006519
• Protein Refseq: NP_006510
• MIM: 601554
• UniProt ID: P63172
• Chromosome Location: 6q25.2-q25.3
• Function: identical protein binding; motor activity; protein binding