Recombinant Human DSN1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: DSN1-1153H
• Product Overview: DSN1 MS Standard C13 and N15-labeled recombinant protein (NP_001138790) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a kinetochore protein that functions as part of the minichromosome instability-12 centromere complex. The encoded protein is required for proper kinetochore assembly and progression through the cell cycle. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc&DDK
• Molecular Mass: 38.1 kDa
• AA Sequence: MSKTHDHQLESSLSPVEVFAKTSASLEMNQGVSEERIHLGSSPKKGGNCDLSHQERLQSKSLHLSPQEQSASYQDRRQSWRRASMKETNRRKSLHPIHQGITELSRSISVDLAESKRLGCLLLSSFQFSIQKLEPFLRDTKGFSLESFRAKASSLSEELKHFADGLETDGTLQKCFEDSNGKASDFSLEASVAEMKEYITKFSLERQTWDQLLLHYQQEAKEILSRGSTEAKITEVKVEPMTYLGSSQNEVLNTKPDYQKILQNQSKVFDCMELVMDELQGSVKQLQAFMDESTQCFQKVSVQLGKRSMQQLDPSPARKLLKLQLQNPPAIHGSGSGSCQTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: DSN1 DSN1 component of MIS12 kinetochore complex [ Homo sapiens (human) ]
• Official Symbol: DSN1
• Synonyms: DSN1; DSN1, MIND kinetochore complex component, homolog (S. cerevisiae); C20orf172, chromosome 20 open reading frame 172; kinetochore-associated protein DSN1 homolog; dJ469A13.2; hKNL 3; kinetochore null 3 homolog (C. elegans); KNL3; MIS13; kinetochore null 3 homolog; hKNL-3; C20orf172; FLJ13346; MGC32987
• Gene ID: 79980
• mRNA Refseq: NM_001145318
• Protein Refseq: NP_001138790
• MIM: 609175
• UniProt ID: Q9H410