Recombinant Human DSC2 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | DSC2-4443H |
Product Overview : | DSC2 MS Standard C13 and N15-labeled recombinant protein (NP_004940) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. |
Molecular Mass : | 93.77 kDa |
AA Sequence : | MEAARPSGSWNGALCRLLLLTLAILIFASDACKNVTLHVPSKLDAEKLVGRVNLKECFTAANLIHSSDPDFQILEDGSVYTTNTILLSSEKRSFTILLSNTENQEKKKIFVFLEHQTKVLKKRHTKEKVLRRAKRRWAPIPCSMLENSLGPFPLFLQQVQSDTAQNYTIYYSIRGPGVDQEPRNLFYVERDTGNLYCTRPVDREQYESFEIIAFATTPDGYTPELPLPLIIKIEDENDNYPIFTEETYTFTIFENCRVGTTVGQVCATDKDEPDTMHTRLKYSIIGQVPPSPTLFSMHPTTGVITTTSSQLDRELIDKYQLKIKVQDMDGQYFGLQTTSTCIINIDDVNDHLPTFTRTSYVTSVEENTVDVEILRVTVEDKDLVNTANWRANYTILKGNENGNFKIVTDAKTNEGVLCVVKPLNYEEKQQMILQIGVVNEAPFSREASPRSAMSTATVTVNVEDQDEGPECNPPIQTVRMKENAEVGTTSNGYKAYDPETRSSSGIRYKKLTDPTGWVTIDENTGSIKVFRSLDREAETIKNGIYNITVLASDQGGRTCTGTLGIILQDVNDNSPFIPKKTVIICKPTMSSAEIVAVDPDEPIHGPPFDFSLESSTSEVQRMWRLKAINDTAARLSYQNDPPFGSYVVPITVRDRLGMSSVTSLDVTLCDCITENDCTHRVDPRIGGGGVQLGKWAILAILLGIALLFCILFTLVCGASGTSKQPKVIPDDLAQQNLIVSNTEAPGDDKVYSANGFTTQTVGASAQGVCGTVGSGIKNGGQETIEMVKGGHQTSESCRGAGHHHTLDSCRGGHTEVDNCRYTYSEWHSFTQPRLGEESIRGHTLIKNTRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name | DSC2 desmocollin 2 [ Homo sapiens (human) ] |
Official Symbol | DSC2 |
Synonyms | DSC2; desmocollin 2; DSC3; desmocollin-2; CDHF2; cadherin family member 2; desmosomal glycoprotein II; desmosomal glycoprotein III; desmosomal glycoprotein II/III; DG2; ARVD11; DGII/III; DKFZp686I11137; |
Gene ID | 1824 |
mRNA Refseq | NM_004949 |
Protein Refseq | NP_004940 |
MIM | 125645 |
UniProt ID | Q02487 |
◆ Recombinant Proteins | ||
DSC2-2534M | Recombinant Mouse DSC2 Protein, His (Fc)-Avi-tagged | +Inquiry |
RFL36737BF | Recombinant Full Length Bovine Desmocollin-2(Dsc2) Protein, His-Tagged | +Inquiry |
Dsc2-2662M | Recombinant Mouse Dsc2 Protein, Myc/DDK-tagged | +Inquiry |
RFL5362MF | Recombinant Full Length Mouse Desmocollin-2(Dsc2) Protein, His-Tagged | +Inquiry |
Dsc2-8753R | Recombinant Rat Dsc2, His tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
DSC2-2051HCL | Recombinant Human DSC2 cell lysate | +Inquiry |
DSC2-1159RCL | Recombinant Rat DSC2 cell lysate | +Inquiry |
Not For Human Consumption!
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