Recombinant Human DPP6 Protein, His tagged

• Cat.No.: DPP6-001H
• Product Overview: Recombinant Human DPP6 Protein (K120-D803, V458E) with His tag was expressed in HEK293T.

Specification

• Species: Human
• Source: HEK293T
• Tag: His
• Protein Length: 120-803 aa
• Description: This gene encodes a single-pass type II membrane protein that is a member of the peptidase S9B family of serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Variations in this gene may be associated with susceptibility to amyotrophic lateral sclerosis and with idiopathic ventricular fibrillation. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 79 kDa
• AASequence: KKIESLRAIRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHWWSPDGTRLAYAAINDSRVPIMELPTYTGSIYPTVKPYHYPKAGSENPSISLHVIGLNGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCDATTGVCTKKHEDESEAWLHRQNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQPNSSNDNIQSITSGDWDVTKILAYDEKGNKIYFLSTEDLPRRRQLYSANTVGNFNRQCLSCDLVENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAINDRQMPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWETVMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVAVFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHYFTSSSLKQHLYRSIINFFVECFRIQDKLPTVTAKEDEEEDHHHHHHHH
• Endotoxin: < 1 EU/μg by LAL
• Purity: >90% estimated by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Sterile PBS, pH7.4, 10% Glycerol, 5% Trehalose
• Concentration: 1 mg/mL by BCA

Gene Information

• Gene Name: DPP6 dipeptidyl-peptidase 6 [ Homo sapiens (human) ]
• Official Symbol: DPP6
• Synonyms: DPP6; dipeptidyl-peptidase 6; dipeptidylpeptidase 6, dipeptidylpeptidase VI; dipeptidyl aminopeptidase-like protein 6; DPPX; DPP VI; dipeptidylpeptidase 6; dipeptidyl peptidase 6; dipeptidylpeptidase VI; dipeptidyl peptidase VI; dipeptidyl peptidase IV-like protein; dipeptidyl peptidase IV-related protein; dipeptidyl aminopeptidase-related protein; dipeptidyl aminopeptidase IV-related protein; VF2; FLJ55680; MGC46605
• Gene ID: 1804
• mRNA Refseq: NM_001039350
• Protein Refseq: NP_001034439
• MIM: 126141
• UniProt ID: P42658