Recombinant Human DPH1 Protein, MYC/DDK-tagged

• Cat.No.: DPH1-2481H
• Product Overview: Recombinant Human DPH1 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is an enzyme involved in the biosynthesis of diphthamide, a modified histidine found only in elongation factor-2 (EEF2). Diphthamide residues in EEF2 are targeted for ADP-ribosylation by diphtheria toxin and Pseudomonas exotoxin A. Defects in this gene have been associated with both ovarian cancer and autosomal recessive intellectual disability with short stature, craniofacial, and ectodermal anomalies.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 48.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: DPH1 DPH1 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: DPH1
• Synonyms: DPH2L; DPH2L1; OVCA1
• Gene ID: 1801
• mRNA Refseq: NM_001383
• Protein Refseq: NP_001374
• MIM: 603527
• UniProt ID: Q9BZG8