Recombinant Human DOT1L Protein, GST-tagged

• Cat.No.: DOT1L-006H
• Product Overview: Recombinant Human DOT1L protein (2-416） with a N-terminal GST-tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes.
• Source: E. coli
• Species: Human
• Tag: GST
• Molecular Mass: 74.1 kDa
• Protein length: 2-416
• Purity: ≥95% estimated by SDS-PAGE
• Stability: ≥ 6 months
• Storage: -80 centigrade

Gene Information

• Gene Name: DOT1L DOT1 like histone lysine methyltransferase [ Homo sapiens (human) ]
• Official Symbol: DOT1L
• Synonyms: DOT1L; DOT1 like histone lysine methyltransferase; DOT1; KMT4; histone-lysine N-methyltransferase, H3 lysine-79 specific; DOT1 like histone H3K79 methyltransferase; DOT1-like histone methyltransferase
  DOT1-like protein; DOT1-like, histone H3 methyltransferase; H3-K79-HMTase; histone H3-K79 methyltransferase; histone methyltransferase DOT1L; lysine N-methyltransferase 4; EC 2.1.1.360
• Gene ID: 84444
• mRNA Refseq: NM_032482
• Protein Refseq: NP_115871
• MIM: 607375
• UniProt ID: Q8TEK3