Recombinant Human DOK5 Protein (1-198 aa), His-SUMO-tagged

• Cat.No.: DOK5-460H
• Product Overview: Recombinant Human DOK5 Protein (1-198 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Partial.

Specification

• Species: Human
• Source: E.coli
• Tag: His&SUMO
• Protein Length: 1-198 aa
• Description: DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assbly of multimolecular signaling complexes. DOK5 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway. Putative link with downstream effectors of RET in neuronal differentiation.
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 38.8 kDa
• AA Sequence: MECVGTRINDISLGEPDLLATGVEREQSERFNVYLMPSPNLDVHGECALQITYEYICLWDVQNPRVKLISWPLSALRRYGRDTTWFTFEAGRMCETGEGLFIFQTRDGEAIYQKVHSAALAIAEQHERLLQSVKNSMLQMKMSERAASLSTMVPLPRSAYWQHITRQHSTGQLYRLQDVSSPLKLHRTETFPAYRSEH
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: DOK5 docking protein 5 [ Homo sapiens ]
• Official Symbol: DOK5
• Synonyms: DOK5; docking protein 5; dJ805C22.1; IRS6; IRS-6; C20orf180; MGC16926
• Gene ID: 55816
• mRNA Refseq: NM_018431
• Protein Refseq: NP_060901
• MIM: 608334
• UniProt ID: Q9P104